YOGA-CF
Research type
Research Study
Full title
Yoga Outcomes Get Assessed in Cystic Fibrosis (YOGA-CF)
IRAS ID
303898
Contact name
Nicholas Simmonds
Contact email
Sponsor organisation
Royal Brompton and Harefield NHS Foundation Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 9 months, 1 days
Research summary
Cystic fibrosis (CF) is a life-limiting genetic condition affecting over 10,900 people in the UK. While currently there is no cure for CF, treatments prevent and manage lung infections which lead to lung failure which is ultimately, the main cause of death. Alongside lung disease, people with CF can experience complications including digestive issues, pain and reduced quality of life.
There is evidence that exercise is beneficial for people with CF. Yoga is a popular activity adopted by many people with CF and those people often associate improvements in breathing, posture, pain and mental health with regular yoga practice. However, despite these reports and evidence for yoga in the general population, evidence for the effect of yoga in CF is scarce.
This study’s primary aim is to investigate the effect of yoga for adults with CF on health-related quality of life. Additionally, we will assess physical measures such as strength, mental health measures such as anxiety and assess the economic cost of yoga against usual care.
Our yoga programme includes breathing exercises, physical yoga poses and mindfulness, designed using focus groups, research and clinical experience. People with CF cannot mix due to infection risks, so we are using an online yoga platform as it provides the opportunity to gather as a group in a safe environment.
Our study will recruit adults with CF from adult CF centres based across the UK. Participants will be randomly put into two groups, either completing yoga classes for 12-weeks (‘intervention’) or a group completing their usual CF care, and no yoga (the ‘control’). Assessments will be completed at the start and end of the 12-week period and then after a further 12-weeks. At the end of the trial, the control group will be offered 12-weeks of yoga to complete independently outside of the study.
REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
23/YH/0270
Date of REC Opinion
23 Jan 2024
REC opinion
Further Information Favourable Opinion