WHISPER-P
Research type
Research Study
Full title
Whole brain Human Ischemic Stroke Perfusion and Extended Recanalisation - Pilot (WHISPER-P)
IRAS ID
216308
Contact name
Keith Muir
Contact email
Sponsor organisation
NHS Greater Glasgow and Clyde
Duration of Study in the UK
1 years, 5 months, days
Research summary
Ischaemic stroke is caused by a blockage in a brain artery. Treatment to dissolve or remove the clot that causes the blockage is effective if started within 4.5 hours after onset of stroke symptoms. Blood flow scans of the brain show, however, that in some people, brain tissue might survive for much longer than this after stroke. Surviving areas may potentially be rescued by restoring blood flow, and very recent information suggests that this might be beneficial in selected people. It is not known in what proportion of people salvageable brain tissue is present at later stages after onset of stroke, so we wish to investigate this using blood flow scanning (with CT Perfusion scans) in people with stroke symptoms between 4.5 and 24 hours earlier. Understanding how many patients have salvageable brain tissue at different time points after their symptoms start is important in guiding future clinical trials that aim to treat patients.
REC name
Scotland A: Adults with Incapacity only
REC reference
18/SS/0001
Date of REC Opinion
8 Feb 2018
REC opinion
Favourable Opinion