VMT-VT-1161-CL-011 - Recurrent Vulvovaginal Candidiasis

  • Research type

    Research Study

  • Full title

    A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of VT-1161 Oral Capsules in the Treatment of Subjects with Recurrent Vulvovaginal Candidiasis

  • IRAS ID

    252990

  • Contact name

    Jonathan Ross

  • Contact email

    jonathan.ross@uhb.nhs.uk

  • Sponsor organisation

    Mycovia Pharmaceuticals

  • Eudract number

    2018-001269-18

  • Clinicaltrials.gov Identifier

    NCT03562156

  • Clinicaltrials.gov Identifier

    NA, NA

  • Duration of Study in the UK

    2 years, 1 months, 0 days

  • Research summary

    This is a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of VT-1161 Oral Capsules in the Treatment of Subjects with Recurrent Vulvovaginal Candidiasis.

    Around 300 subjects at approximately 80 study centres in North America, Europe, and Japan will take part in this study. There will be 3 centres in the UK.

    This study is for nonpregnant females aged 12 years or older that have been diagnosed with recurrent yeast infections. This is a Phase 3 study, which means that the study drug has been investigated in previous studies involving smaller groups of people with recurrent vulvovaginal candidiasis, sometimes called “recurrent yeast infection.”

    The purpose of this research study is to see how safe the study drug (VT-1161) is, how well it works, and how it effects the quality of life in people with recurrent yeast infections.

    The participant and study doctor will not know if the participant is receiving the study drug or placebo (this is called a “blinded study”).

    Participation in this research study will last for approximately 50 weeks.

    The Sponsor of this study is Mycovia Pharmaceuticals.

  • REC name

    East Midlands - Nottingham 2 Research Ethics Committee

  • REC reference

    18/EM/0384

  • Date of REC Opinion

    8 Jan 2019

  • REC opinion

    Further Information Favourable Opinion