Vitamin D & PCOS
Research type
Research Study
Full title
The effect of colecalciferol (Vitamin D) on hormonal, metabolic and cardiovascular risk factors in women with polycystic ovary syndrome (PCOS) – a double blind randomised placebo-controlled study
IRAS ID
156443
Contact name
Thozhukat Sathyapalan
Contact email
Sponsor organisation
Research & Development Department, Hull & East Yorkshire Hospitals NHS Trust
Research summary
Polycystic ovary syndrome (PCOS) is a very common condition in women which could present with irregular periods, excessive hair growth on body, acne and cysts in the ovaries.
PCOS is also associated with increased risk of problems later in life like diabetes, high cholesterol levels and heart disease. One of the risk factors for having increased incidence of such problems in PCOS patients could be low vitamin D levels as many women with polycystic ovary syndrome (PCOS) are vitamin D deficient. Vitamin D supplementation may have a beneficial effect on insulin levels. It has been seen in previous research studies that low level of vitamin D is related to a greater risk of diabetes and heart disease. So, in this study we want to supplement women having PCOS and vitamin D deficiency with vitamin D (3,200 IU) and examine the effects on hormones related to PCOS and risk factors for diabetes and heart disease in them.REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
14/YH/1125
Date of REC Opinion
19 Sep 2014
REC opinion
Further Information Favourable Opinion