Verifying the effect of DOAC-Stop on plasma
Research type
Research Study
Full title
Verifying the effect of DOAC stop on plasma where there is a need to rule in/out causes of prolongation in coagulation screen results.
IRAS ID
325879
Contact name
CLAIRE ROWLANDSON
Contact email
Sponsor organisation
Blackpool Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 3 months, 0 days
Research summary
The aim of the study is to establish whether DOAC-stop reagent can successfully neutralise direct oral anticoagulants (DOACs) in patient’s pre-operative assessment coagulation samples, therefore removing the requirement of a patient to stop their anticoagulant therapy prior to pre-operative assessment and reduce the need for further specialist coagulation testing due to interference from DOACs.
The advantages of this would be patient safety as the patients would not have to stop their DOACs before their preoperative assessment, reduce cancellations of patients’ surgery reducing the risk of harm caused to patients due to delays and reduce the workload for the haematology department as specialised tests would not need to be undertaken within a quick turnaround time.REC name
East Midlands - Derby Research Ethics Committee
REC reference
23/EM/0154
Date of REC Opinion
27 Jul 2023
REC opinion
Further Information Favourable Opinion