Validation assay for urinary leukotriene E4 and prostaglandin E2

• Research type

  Research Study

• Full title

  Validation assay for urinary leukotriene E4 and prostaglandin E2

• IRAS ID

  324417

• Contact name

  Malcolm Marquette

• Contact email

  m.marquette@uea.ac.uk

• Sponsor organisation

  Norwich Medical School, University of East Anglia

• Duration of Study in the UK

  0 years, 4 months, 1 days

• Research summary

  The purpose of this study is to provide deliverables to be generated during the fit-for-purpose verification of the Cayman Leukotriene E4 (LTE4) and Prostaglandin E2 (PGE2) assays using anonymized random urine.
  LTE4 assay is provided fully validated by Cayman Chemical (Ann Arbor, Michigan; cat#501060). PGE2 assay is provided fully validated by the R&D system (Bio-Techne, Abingdon, UK). The aim of this verification is to ensure the kits perform as per manufacturers’ claims and in line with the Bioanalytical Facility quality policy.
  These will include Kit performance, spiked recovery, linearity of dilution, reproduciblility and stability

• REC name

  London - West London & GTAC Research Ethics Committee

• REC reference

  23/PR/0068

• Date of REC Opinion

  16 Feb 2023

• REC opinion

  Further Information Favourable Opinion