Vaginal Hysterectomy in patients with a non-prolapsed large uterus,
Research type
Research Study
Full title
ERBE Biclamp Vaginal Hysterectomy in patients with a non-prolapsed large uterus, a retrospective cohort study comparing postoperative outcomes.
IRAS ID
184175
Contact name
Colin Prendergast
Contact email
Sponsor organisation
Western HSC Trust
Duration of Study in the UK
0 years, 0 months, 29 days
Research summary
In this study we wish to determine whether there is a significant difference in outcome between patients with a non-prolapsed large uterus undergoing Biclamp vaginal hysterectomy compared with patients with a non-prolapsed normal sized uterus.
When compared with abdominal hysterectomy, vaginal hysterectomy has been associated with fewer complications and a shorter length of hospital stay making it the preferred approach. Traditionally it was felt that a large uterus (>12 week size or >280g) was a contraindication to vaginal hysterectomy. Recently however there have been a number of studies challenging this perception. If we can safely perform a vaginal hysterectomy in patients with a large uterus this would reduce the risk of complications, lead to a shorter hospital stay and reduce the cost to healthcare services.
Using theater lists we will identify patients who underwent Biclamp Vaginal Hysterectomy between 2010 and 2013 under the care of Dr Prendergast. We will exclude patients who underwent hysterectomy for prolapse or who had additional procedures performed. For the patients identified we will access pathology records in order to obtain information on uterine size. Every patient with a uterus >280g will be assigned to the ‘large uterus’ cohort. Patients with a uterus <280g will be randomly selected for the control group using random number allocation.
From both the cohort and control groups we will obtain information on pre-operative factors such as BMI, parity, previous abdominal surgery, age, medical co- morbidity and previous caesarean section. We will also record post-operative outcomes such as estimated blood loss, duration of surgery, surgical complications, duration of post op stay, readmission and outcome at review 6 weeks following surgery.REC name
HSC REC A
REC reference
15/NI/0143
Date of REC Opinion
8 Jul 2015
REC opinion
Favourable Opinion