Uveitic ADS Study
Research type
Research Study
Full title
The contribution of altered aqueous dynamics in the development of raised intraocular pressure in patients with uveitis
IRAS ID
136787
Contact name
K. Sheng Lim
Contact email
Sponsor organisation
North Essex Partnership University NHS Foundation Trust
Research summary
Uveitis is the cause of visual impairment in 10% of the registered UK blind population, and some of this population are at risk of further visual loss from the development of uveitic glaucoma. Uveitic glaucoma is much more difficult to treat compared with other types of glaucoma, partly because very little is known about the pathogenesis of this condition. This study aims to assess the relative contribution of either drainage pathway obstruction and/or changes in aqueous production rate to the development of raised intraocular pressure in different types of uveitis. There is currently no standard treatment regime for uveitic glaucoma, and preference for particular class of drug or type of surgeries is generally an anecdotal decision.
This will be the first study of this kind addressing the specific effect of uveitis on aqueous humour dynamic. It will lead to a better understanding of this potentially blinding condition and allow clinicians to develop better treatment strategies for these patients in order to preserve their sight.
REC name
London - Bromley Research Ethics Committee
REC reference
13/LO/1249
Date of REC Opinion
18 Sep 2013
REC opinion
Further Information Favourable Opinion