Utility of ROTEM in measuring hypercoagulability in COVID-19 patients.
Research type
Research Study
Full title
Prospective observational study to evaluate utility of rotational thromboelastometry in identifying and tracking hypercoagulability in COVID-19 patients.
IRAS ID
284755
Contact name
Sophia Stanford
Contact email
Sponsor organisation
Hampshire Hospitals NHS Foundation Trust
Duration of Study in the UK
1 years, 6 months, 31 days
Research summary
Abnormal coagulation parameters have been noted in patients with COVID-19 and are associated with poor outcome, but we do not know how to use all the individual coagulation parameters to risk stratify patients or if they can be of value in predicting those at risk of thrombosis
Routine coagulation tests are limited in their ability to represent physiological haemostasis as they use cell depleted plasma and only represent certain aspects of the coagulation process. To overcome this limitation rotational thromboelastometry (ROTEM) has been developed and provides a global assessment of coagulation in whole blood.
This study will measure ROTEM parameters and assess whether or not these are predictive of thrombosis and clinical outcome.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
20/EE/0151
Date of REC Opinion
2 Jun 2020
REC opinion
Unfavourable Opinion