Use of oxygen in acute heart failure: pilot inpatient study, OXY-AHF
Research type
Research Study
Full title
Randomised, crossover control trial on the use of oxygen in acute heart failure: pilot inpatient study, OXY-AHF
IRAS ID
207832
Contact name
Parin Shah
Contact email
Sponsor organisation
Hull University Teaching Hospitals NHS Trust
Eudract number
2016-003766-53
Duration of Study in the UK
0 years, 2 months, 28 days
Research summary
Heart failure is a condition where the heart does not have enough strength. This prevents blood from being pumped around the body efficiently. This in turn means that not enough oxygen and nutrients are supplied throughout the body. Due to this, you may experience symptoms such as shortness of breath or fatigue which limits how well you can exercise.
The use of oxygen in patients with heart failure continues to be debated. Oxygen is instinctively used when patients present with shortness of breath despite blood oxygen levels being normal. This is even more common when patients are admitted due to worsening of their condition. But there have been mixed results on its use in patients with heart failure.
We would therefore like to study the use of short term oxygen on the heart function of patients whilst in our hospital. The aim is to find out if increased oxygen supply improves the heart function. Patients who are admitted with a worsening of their condition (heart failure) will be eligible within the first 1-2 days of their admission.
Eligible patients will have all their regular treatment continued. Each patient will be given three different strengths of oxygen, which are usually used when patients are short of breath, in random order for 15 minutes each . Their heart function, oxygen levels and blood pressure will be monitored continuously using two finger probe devices and a blood pressure machine. This will be conducted in one session lasting 3 hours involving half an hour between each oxygen strength.REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
17/YH/0053
Date of REC Opinion
22 Mar 2017
REC opinion
Unfavourable Opinion