Use of NIR imaging to detect and sample early liver metastases.
Research type
Research Study
Full title
The use of NIR imaging to detect and analyse radiologically occult micrometastasatic disease in patients undergoing surgical resection of colorectal liver metastases
IRAS ID
191506
Contact name
Srikanth Reddy
Contact email
Sponsor organisation
Oxford University Hospitals NHS Foundation Trust
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
We are recruiting patient volunteers with bowel cancer which has spread to the liver and who are due to undergo surgery to remove the liver tumours. If you volunteer for this project we will ask you to come into hospital 24 hours before your operation.
Many patients who develop bowel cancer die because the cancer has spread to the liver. We aim to use a novel technique to detect liver tumours at an earlier stage. Currently, we are able to detect only very obvious tumours within the liver and remove them by surgery. Our new technique involves injecting a dye into the blood of patients so that much smaller tumours can then be seen by a special camera and removed during the operation.
If you agree, any tumours which are removed will also be studied in the laboratory enabling us to better understand the processes leading to the spread of bowel cancer.
Your operation will take place at an NHS hospital where this surgery is routinely carried out. Since the tumours will be extremely small the additional risk of this new technique will be negligible. Your involvement in the project will end when your operation is complete.
REC name
South Central - Berkshire B Research Ethics Committee
REC reference
16/SC/0455
Date of REC Opinion
1 Nov 2016
REC opinion
Further Information Favourable Opinion