Use of donor immune cells to research reactivity V1

• Research type

  Research Study

• Full title

  Use of donor immune cells to research antigen reactivity

• IRAS ID

  294092

• Contact name

  Sean Russell

• Contact email

  s.russell@achillestx.com

• Sponsor organisation

  Achilles Therapeutics UK Ltd

• Clinicaltrials.gov Identifier

  n/a, n/a

• Duration of Study in the UK

  4 years, 11 months, 30 days

• Research summary

  The project aims to understand how immune cells recognise and respond to tumours. This will help to develop cell therapies and vaccines for cancer. The project will use blood from anonymised healthy donors or cancer patients that is collected by commercial providers or surplus from blood donations. The immune cells will be cultured with short protein sequences (peptides) to explore which cells respond. The results will be used to infer how cells react to tumour peptides and how this can be predicted and optimised.

• REC name

  Wales REC 6

• REC reference

  21/WA/0117

• Date of REC Opinion

  9 Apr 2021

• REC opinion

  Favourable Opinion