Use of continous glucose monitoring in post cardiac surgical patients
Research type
Research Study
Full title
A PILOT STUDY TO ASSESS THE SAFETY AND RESOURCE UTILISATION OF CONTINUOUS INTRAVENOUS GLUCOSE MONITORING IN POST CARDIAC SURGICAL PATIENTS
IRAS ID
136233
Contact name
Nigel Scawn
Contact email
Sponsor organisation
Liverpool Heart and Chest Hospital NHS Foundation Trust
Research summary
The aim of this study is to explore whether tight control of blood glucose within normal range is achievable and safe with a device that continually measures blood sugar concentration. This is of great importance as it is well known that poor control of blood glucose has many detremental effects. The pilot study will be conducted on 100 sequential patients undergoing cardiac surgery at Liverpool Heart and Chest Hospital, and will involve the measurement of blood glucose immediately prior to surgery and for 72 hours intra and post-operatively. These blood samples are taken from a small cannula inserted into the patient’s vein, which is attached to a device called GlucoClear which displays the result. The sampled blood is then returned to the patient. This device is manufactured by Edwards Lifesciences and is already licensed for use in the normal clinical environment.
The main aim of the study is to demonstrate that maintenance of blood glucose within normal limits is easily achievable, defined as having at least 90% of recorded values within the reference range of 4.4 - 8.0 mmol/L. By the avoidance of very low or high blood glucose measurements we also aim to demonstrate improvements in patient care, including a reduction in patient length of stay, incidence of complications such as renal failure and infection, and a potential reduction in mortality rate. By reducing the rate of many of these complications, we also hope to show a potential economical benefit by the use of continual blood glucose monitoring.REC name
North West - Liverpool Central Research Ethics Committee
REC reference
13/NW/0611
Date of REC Opinion
23 Sep 2013
REC opinion
Further Information Favourable Opinion