Urine Acidification of Clinical Samples.
Research type
Research Study
Full title
Urine acidification: outdated practice or a clinical laboratory requisite?
IRAS ID
262398
Contact name
Ravinder Sodi
Contact email
Sponsor organisation
University Hospitals of Morecambe Bay NHS Foundation Trust
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
0 years, 11 months, 27 days
Research summary
This study aims to investigate whether urine collections need to be taken into bottles containing acid as a preservative for a number of commonly requested tests in clinical laboratories, such as calcium, magnesium, phosphate and copper. It has been suggested that urine acidification is crucial for analyte stability; however, recent evidence suggests otherwise. In addition, acid in bottles carries huge health and safety risks to both patients and staff. By comparing the concentrations of the stated analytes in bottles, with and without acid, this study will help determine whether this practice is necessary in a modern laboratory.
REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
19/SW/0125
Date of REC Opinion
16 Sep 2019
REC opinion
Further Information Favourable Opinion