Upper limb stroke rehabilitation via the VirtualRehab platform (v.1)
Research type
Research Study
Full title
Task-orientated training via the VirtualRehab platform for the upper limb after stroke: Feasible dose and predictive markers of response
IRAS ID
233548
Contact name
Fiona Ellis
Contact email
Sponsor organisation
University of East Anglia
Duration of Study in the UK
1 years, 5 months, 1 days
Research summary
A key priority identified by health services and people with stroke is to deliver evidence-based stroke rehabilitation to achieve optimal levels of upper limb function, with increasingly pressured resources. Preliminary investigation suggests technology based rehabilitation elicits promising brain recovery. Current understanding is limited, however, in part due to the variety of ways a stroke affects the individual. Further investigation is needed to ascertain whether, in particular, non-immersive virtual rehabilitation has a biological rationale for expecting clinical benefit. Before this can be tested, information is needed to determine how many weeks (dose) of such an intervention is required for a clinically relevant change; and which people with stroke could show the greatest benefit (predictive markers). In addition, the feasibility of conducting a randomised control trial (RCT) requires investigation.
Therefore, this study will carry out 12 weeks of an exercise-based upper limb training programme, delivered via the VirtualRehab platform in the homes of 15 people with stroke. After a randomised control period of between 1 to 4 weeks long. To address the research objectives measurements will take place at baseline-one; baseline-two (after the control phase); every week of the intervention (progress measures) and the outcome. In addition, interviews will explore the feasibility of the study design and acceptability of the home-based task-orientated training.
Participants’ neural function, motor impairment and functional ability will be measured with non-invasive valid and reliable measures. Neural function will be measured using Electromyography-derived measures (EMG). Motor impairment will be measured with a Myometer and, within participants’ homes, the Motricity Index (MI). In addition, functional ability will be measured with the Wolf Motor Function Test (WMFT) and, at home, the Action Arm Research Test (ARAT). Finally, to provide comparative neural function data from a neurologically-intact brain, ten additional participants will be recruited to undertake the neural measures.
REC name
London - Surrey Research Ethics Committee
REC reference
18/LO/0562
Date of REC Opinion
3 May 2018
REC opinion
Further Information Favourable Opinion