Univation X Partial Knee Study
Research type
Research Study
Full title
Univation X: A functional and clinical outcomes study of a partial knee replacement
IRAS ID
240087
Contact name
Alistair M Ewen
Contact email
Sponsor organisation
Golden Jubilee Foundation
Duration of Study in the UK
4 years, 0 months, 24 days
Research summary
This is an assessment of the functional and clinical outcomes after medial unicompartmental knee joint replacement using the Univation X knee prosthesis. The reported benefits of having a unicompartmental knee arthroplasty (UKA) compared to a total knee arthroplasty (TKA) are less invasive surgery, less post-operative pain, quicker recovery, shorter length of inpatient stay, preservation of the anterior cruciate ligament, better knee function and a lower risk of complications. However, there is very little data on the biomechanical functional outcomes of patients who have undergone UKA, and the data that is available focuses on level walking. It is thought that more challenging activities may be required to fully unveil changes to a person's movement patterns due to arthritis and subsequent joint replacement. The challenging activities we plan to observe mirror those which most patients will encounter as part of everyday life: sitting into and rising from a chair, stepping on and off a step, walking on an incline or decline and level walking, and single leg balance. We plan to evaluate these activities using 3D motion analysis before and after surgery and then compare the measurements to a data set from a group of healthy controls. This will allow us to observe any improvements in the patient's movement patterns following surgery and also compare them to the movement patterns of an age-matched control group. We will also investigate the position and orientation of the implant through the use of CT scans. The clinical outcomes we will be x-rays and questionnaires (for the patient's satisfaction, pain and functional abilities).
REC name
South East Scotland REC 02
REC reference
19/SS/0021
Date of REC Opinion
22 Feb 2019
REC opinion
Favourable Opinion