Understanding psychological distress in LVAD recipients.
Research type
Research Study
Full title
Adjusting to Life with a Left Ventricular Assist Device (LVAD): The mediating effects of self-compassion and psychological flexibility on the relationship between LVAD acceptance and psychological distress.
IRAS ID
333369
Contact name
Rachel McGowan
Contact email
Sponsor organisation
University of Liverpool
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
A left ventricular assist device (LVAD) is a mechanical pump that supports physiological function by offering circulatory support for individuals with advanced heart failure. The development of mechanical support devices has contributed to considerable improvements in the treatment of heart failure.
Many difficulties accompany life with an LVAD. System checks, charging and swapping of batteries, having an awareness of alarms and being competent in driveline dressing changes are all necessary. Such changes can affect many or all aspects of a person’s life, including roles within society or relationships, ability to work, hobbies or enjoyable activities. Therefore, people can feel as though they are unable to live a valued life, or they lose touch with their identity. When someone struggles to accept and adjust to such, it is more likely that they will feel discontent towards their LVAD and experience mental health difficulties, such as an increase in anxiety or depression.
Recent research has found that a quarter real-world stable patients living with an LVAD experience clinically relevant levels of depression and anxiety. Research attributes this elevated psychological distress to poor device acceptance. This research proposes the need to corroborate this finding, in addition to understanding the mechanisms that may contribute to device acceptance. This research therefore aims to assess the possible mediating effects of self-compassion and psychological flexibility on the relationship between device acceptance and depression and anxiety. Understanding the role of these psychological constructs will broaden our understanding of what psychological support can be offered those living with an LVAD in a safe and effective way.
This research will aim to recruit 116 people living with an LVAD from five NHS sites. Recruitment is estimated to take 12 months.
REC name
London - Dulwich Research Ethics Committee
REC reference
24/PR/0331
Date of REC Opinion
3 Apr 2024
REC opinion
Favourable Opinion