UKYSS

  • Research type

    Research Study

  • Full title

    The United Kingdom Young Stroke study - an ambispective observational study exploring the demographics, risk factors, investigation and outcomes of ischaemic and haemorrhagic strokes in patients aged 18-49 years old in the United Kingdom

  • IRAS ID

    321270

  • Contact name

    Phillip Ferdinand

  • Contact email

    phillip.ferdinand@uhnm.nhs.uk

  • Sponsor organisation

    Keele University

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    10-15% of strokes occur in the young which is defined as 18-50 years old. The UK has over 100,000 strokes annually and approximately 10,000 will be young. Overall, the death rate from strokes is declining in the UK. However, the amount of strokes in the young is increasing and there is urgent need to understand the reason for this.

    UKYSS is a study that will determine the number, characteristics, risk factors and long term outcomes in young strokes in the UK. Participants are identified from entries in the Sentinel Stroke Audit Program and they will be asked questions about life after their stroke and information from their medical records obtained.

    The information will then be analysed and examined for differences between age, sex and ethnic minority. The analysis will then move on and aim to create a prediction model for the risk of stroke and mortality at 5 years after the original stroke. The study will also identify what factors put an individual at a higher risk.

    It is important to understand young strokes in the UK, with its diverse population, for what is an increasing public health problem with significant long term consequences. This will allow the development of targeted public health interventions and improve training and awareness of health care professionals.

  • REC name

    South Central - Berkshire Research Ethics Committee

  • REC reference

    23/SC/0145

  • Date of REC Opinion

    22 May 2023

  • REC opinion

    Favourable Opinion