UK infection and cystine stone follow-up - V1.
Research type
Research Study
Full title
Long term longitudinal follow-up study of infection stone and cystine stone patients in the UK.
IRAS ID
187164
Contact name
Bhaskar Somani
Contact email
Duration of Study in the UK
0 years, 4 months, 8 days
Research summary
It has become clear that over the past forty years the overall incidence of kidney stones has consistently increased, with the recurrence rate for stones being 50% within 5-10 years and 75% within 20 years. As well as increased incidence, it has been noted in other countries that that the composition of stones and the demographics of stone patients appears to be changing over time. The exact reasons for these changes are yet to be determined and this area has therefore been deemed to merit further investigation by other recent studies. Moreover there is a lack of up-to-date evidence of the described changes themselves (patient demographics, stone constituents) in a UK population, and more specifically a lack of current research associated with struvite/infection stones and cystine stones (such as methods of presentation, co-morbidities, changes in management, best practice for management, and follow-up).
We therefore aim to create a set of data from medical records going back 20 years and looking at a number of different aspects of stone disease and stone management in relation to cystine and infection/struvite stones. We hope that this up-to-date, UK relevant data set might provide local/UK clinicians with a greater understanding of the changes in this area of stone disease management and be taken into account when discussing best practice for management of these patients (particularly recurrent stone-formers).
REC name
London - Surrey Research Ethics Committee
REC reference
15/LO/1387
Date of REC Opinion
4 Aug 2015
REC opinion
Favourable Opinion