UCL Infection DNA Bank 2022

• Research type

  Research Tissue Bank

• IRAS ID

  320050

• Research summary

  UCL Infection DNA Bank 2022

• REC name

  London - Fulham Research Ethics Committee

• REC reference

  23/LO/0238

• Date of REC Opinion

  23 May 2023

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  The UCL Infection DNA Bank will collect and store DNA/RNA to undertake research to analyse the genetic basis for infectious diseases affecting humans. It is intended that both microbial and human DNA will be analysed. The DNA bank will use residual diagnostic samples, identified with a unique identification number to provide opportunity to consent participants to request further samples and information.
  Samples identified as Non-relevant under the human tissue act will be collected including:Existing holdings of residual diagnostic samples (non-consented) and research samples or data collected with consent.
  Samples will be stored in the UCL-RFH BioBank or in locally named freezers. Records of the locations of local storage will be kept with the DNA Bank coordinator.
  Number of samples stored, accrued annually and used and destroyed to be reported on a quarterly basis to the DNA Bank Coordinator.
  Pseudonymised data will be held securely within an Information Data Safe Haven under the custodianship of the chief investigator. Data collected with consent will be held within the Data Safe Haven in a separate location in accordance with the HRA CAG application.

• Research programme

  The DNA bank will support researchers investigating human infectious diseases. The primary research interest of the applicant is virology, however this important resource will be used more widely to encompass a range of human diseases. These analyses will include experiments to identify specific changes in DNA, RNA and proteins that can be related to disease. All research will be healthcare related, using basic translational and clinical research approaches.

• Storage license

  11016

• RTBTitle

  UCL Infection DNA Bank 2022

• Establishment organisation

  University College London

• Establishment organisation address

  Gower Street

  London

  WC1E 6BT