Trimodal Prehabilitation for aneurysm surgery study (T-PASS)
Research type
Research Study
Full title
Maximising Recovery to Health through Trimodal (Bio Psycho Social) Prehabilitation for Aneurysm Surgery Study (T-PASS).
IRAS ID
156200
Contact name
Colin Bicknell
Contact email
Sponsor organisation
Imperial College London Clinical Research Office
Research summary
Prehabilitation aims to enhance an individual’s functional capacity before operation for better tolerance of the surgical burden and faster recovery. There is some emerging evidence that prehabilitation may be important in enhancing post-operative recovery, however, there are as yet no studies within aortic surgery – where the patients are known to have significant co-morbidity from the outset.
There is an opportunity whilst these patients are undergoing dedicated assessment and optimisation for surgery (2-6 weeks before the procedure), to improve their physical, psychological and social fitness in preparation for surgery.
The aim of this study is to evaluate the acceptability and pre-operative impact on functional capacity of a trimodal prehabilitation program in a cohort of patients undergoing aneurysm repair. This will enable the design (feasibility and power) of a large scale Randomised Controlled Trial.
Proposed intervention – The introduction of a biopsychosocial intervention before surgery. The physical exercise programme will be a prescribed exercise training twice per week which will be supported by a qualified physical therapist as well as our vascular nurse specialist. A clinical psychologist will also deliver a brief psychological intervention based on cognitive behavioural therapy (CBT) techniques in two sessions to modify illness, surgical preparation and rehabilitation beliefs. Lastly patients will be counselled and referred to smoking cessation services as appropriate.
Baseline information will include patient demographics and medical history, quality of Life assessment using SF-36 forms, hospital anxiety and depression scale (HADS) and exercise testing by a standardised 6-minute walk test. Information immediately pre-operatively will be collected to include a repeat assessment of physical function with a 6-minute walk test, SF-36 assessment and HADS scores. Smoking cessation rate will be collected.
A pre and post-intervention group will be studied over a 1-year period. We will report on the eligibility, acceptability and pre-operative effect of this trimodal rehabilitation programme.
REC name
London - Fulham Research Ethics Committee
REC reference
14/LO/1368
Date of REC Opinion
22 Sep 2014
REC opinion
Further Information Favourable Opinion