Treating DM Lipohypertrophy: Intensive Education vs Standard Care
Research type
Research Study
Full title
Treating Diabetic Lipohypertrophy with Intensive Education vs Standard Care: A Randomized, Prospective, Controlled Study in Ealing, United Kingdom
IRAS ID
167263
Contact name
Grace Vanterpool
Contact email
Sponsor organisation
BD
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 8 months, 28 days
Research summary
Past studies have shown that long-term insulin usage can lead to changes in the fatty tissue below the skin surface at injection sites. Small nodules or swollen areas can appear which may adversely affect the absorption of insulin. These nodules/swellings are called ‘lipohypertrophy’ (or colloquially called ‘lipos’), which means ‘disorders of fat tissue’. They are not malignant and do not behave like tumours. We still do not know what causes lipos or the best way to prevent and/or treat them. Lipos cause insulin absorption to be delayed or become erratic and unpredictable and patients who have them have worse glucose control, have more hypoglycaemia and consume excessive quantities of insulin. The objective of this study is to determine whether an alternative approach to treating lipos (intensive education, site rotation and shorter needles) is equal to, better than or worse than our usual approach (standard care).
REC name
London - Chelsea Research Ethics Committee
REC reference
14/LO/1997
Date of REC Opinion
4 Feb 2015
REC opinion
Further Information Favourable Opinion