Transcutaneus Posterior Tibial Nerve Stimulation v.1.0
Research type
Research Study
Full title
A single-blind, randomised, controlled trial to evaluate the effectiveness of Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) in Overactive Bladder symptoms in women responders to Posterior Tibial Nerve Stimulation (PTNS).
IRAS ID
127118
Contact name
Carol Shacklady
Contact email
Sponsor organisation
Manchester Metropolitan University
Research summary
Patients suffering from idiopathic Overactive Bladder syndrome and who are refractory to conservative regimens can benefit from Percutaneus Tibial Nerve Stimulation (PTNS), which is a form of peripheral Neuromodulation therapy. Its efficacy has been reported to be comparable to that of the antimuscarinic agents, with an objective success rate of 60%, but with a better side effect profile.
A disadvantage of the use of PTNS is the need for repeated treatments to maintain the symptom improvement.
The aim of this study is to determine the effect of a home-based, patient-delivered transcutaneus posterior tibial nerve stimulation (TPTNS) protocol in OAB symptoms and QoL in women with idiopathic OAB who have responded positively to PTNS.
The potential benefits of the use of TPTNS as oppossed to PTNS is the reduction in costs for the NHS (no need for repeated Hospital visits PTNS); puts the individual in control of their care and promotes health focused behaviour, as this treatment modality is performed at home by the patient; reduction of minor adverse side effects occasionally associated with PTNS.
The study will be a prospective, randomized, single-blind, controlled trial and we will aim to recruit females over 18 years old, diagnosed of idiopathic OAB and who have had a positive response to PTNS.
Participants will be recruited from the Physiotherapy Department at the Liverpool Women’s Hospital.REC name
North West - Liverpool Central Research Ethics Committee
REC reference
13/NW/0826
Date of REC Opinion
16 Dec 2013
REC opinion
Further Information Favourable Opinion