Trace Element Malnutrition in Paediatric Renal Disease
Research type
Research Study
Full title
Micronutrient status in children with kidney disease: Trace element malnutrition in Paediatric Renal Disease (TEMPeReD)
IRAS ID
193238
Contact name
Caroline Anderson
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
0 years, 10 months, 30 days
Research summary
Children with kidney disease have limited diets; caused by reduced appetite, nausea, and food restriction. Good nutrition can help growth and development; and helps kidneys work well - delaying need for dialysis and transplantation. We know that children with kidney disease are unlikely to get enough nutrients from their diets. Giving nutrients is difficult because many supplements have too much of some nutrients, which could build up in the body and cause problems. There is no cure for kidney disease, diagnosis is rapidly increasing in children, and once adults cost the NHS a lot of money. Hopefully, improving nutrition as a child can help both children and adults with kidney problems stay better for longer.
We want to find out:
• how many children are at risk of poor nutrient intake at University Hospital Southampton
• which of these children may benefit from using Renarite (a new kidney specific vitamin and mineral powder)
• if children like Renarite and are able to take it everyday
• if Renarite helps meet the nutritional needs of these children
We will look at 60 children with kidney problems at University Hospital Southampton. 15 children who are at risk will be asked to take Renarite as a drink once-a-day for three months.
Families will be asked detailed questions on their appetite and quality of life, and an extra 5mls (1tsp) of blood taken to check vitamin and mineral amounts when their usual bloods are taken. These same tests will repeated after 3 months for the 15 children who take Renarite.
Families’ answers will help us understand what it is like to have a restricted diet as well as how they feel about living with a kidney problem. The extra blood will see what the body stores of vitamins and minerals are like for children with kidney problems.REC name
London - Surrey Research Ethics Committee
REC reference
16/LO/0041
Date of REC Opinion
4 Feb 2016
REC opinion
Further Information Favourable Opinion