Tooth Tissue Bank BDH V1

• Research type

  Research Tissue Bank

• IRAS ID

  208956

• Research summary

  Tooth Tissue Bank at Bristol Dental Hospital

• REC name

  HSC REC A

• REC reference

  16/NI/0192

• Date of REC Opinion

  29 Sep 2016

• REC opinion

  Favourable Opinion

• Data collection arrangements

  The tooth tissue bank collects and stores teeth from adults and children (aged 6-17). All teeth are collected with informed consent from patients who are attending their dentist or an oral surgery clinic to have teeth removed as part of their routine clinical care. Patients who are going to have teeth extracted are asked by a member of the dental care team whether they would like to keep their teeth after extraction, or whether they would consider donating them to the tooth tissue bank (TTB). Patients who are happy to consider donation of their teeth are given an information sheet (information sheets for children are worded appropriately to the age of the child, with pictures where this is helpful). Any patients who agree to donate their teeth to the TTB are asked to initial the boxes on the consent form and sign it. For children under 16, their parent
  or guardian is also asked to sign.

  The tooth bank does not collect or store any patient data, and all teeth are fully anonymised at the time of collection

• Research programme

  As a teaching hospital and a University school we and our collaborators need human teeth for research projects and to train student dentists. Some projects are designed to understand the nature of teeth, their characteristics and changes that can occur in diseased states. The more we understand about healthy and diseased teeth, the better able we are to design treatment options/oral healthcare products. Other projects are designed to determine the relative abilities of agents to cause damage to teeth, so that the people can be educated about the potential harm certain drinks or foods may do to their dentition. Additionally this information can be used by the suppliers of these products so that they can make formulation changes to limit the damage caused by their products. Teeth are also used in experiments to study potential new ingredients for oral health care products or in trials to test how well new or existing oral hygiene products work, for example toothpastes designed to treat dental hypersensitivity, or to promote enamel remineralisation. A small number of teeth may be released to the Department of Archaeology and Anthropology at the University who compare these 'modern' teeth with archaeological teeth to learn about past habits and practices.

• Storage license

  12200

• RTBTitle

  Tooth Tissue Bank at Bristol Dental Hospital

• Establishment organisation

  University of Bristol

• Establishment organisation address

  Senate House, Tyndall Avenue, Clifton

  Bristol

  BS8 1TH