Titan Reverse Shoulder CP-0960-001

  • Research type

    Research Study

  • Full title

    A post-market clinical follow-up study of the TITAN Reverse Shoulder System used in primary or revision total shoulder arthroplasty

  • IRAS ID

    244782

  • Contact name

    Marilyne Blanc

  • Contact email

    marilyne.blanc@integralife.com

  • Sponsor organisation

    Smith & Nephew

  • Clinicaltrials.gov Identifier

    NCT02204228

  • Duration of Study in the UK

    11 years, 6 months, 2 days

  • Research summary

    Conditions that lead to shoulder replacement include osteoarthritis, rheumatoid arthritis, post-traumatic arthritis, rotator cuff tear arthropathy, avascular necrosis, and severe fractures. Reverse shoulder arthroplasty was first introduced in the 1970’s in response to the difficulty in treating patients with rotator cuff tear arthropathy. The Integra® TITAN™ Reverse Shoulder System (TRS) is a semi-constrained total shoulder construct. When used under the conditions and purposes intended, the TRS may relieve pain and restore functional joint motion to the affected shoulder. The purpose of this study is to assess the short (2-year), mid (5-year) and long term (10-year) outcomes of the TRS. This is a multi-center, prospective, post-market clinical follow up study. The study follow-up is for 10 years and 150 shoulders will be enrolled. Up to 15 investigational sites will participate in this study. Each site will enroll up to 45 subjects.

  • REC name

    London - Westminster Research Ethics Committee

  • REC reference

    18/LO/1188

  • Date of REC Opinion

    23 Aug 2018

  • REC opinion

    Further Information Favourable Opinion