The TITAN Study
Research type
Research Study
Full title
The Next Leap in Cardiac Magnetic Resonance Imaging: Cycling the Field - The TITAN Study
IRAS ID
277272
Contact name
Dana Dawson
Contact email
Sponsor organisation
University of Aberdeen
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
2 years, 11 months, 31 days
Research summary
Aberdeen scientists are at the forefront of a new type of magnetic resonance imaging (MRI), having built in-house the only two available prototypes of Fast Field-Cycling MRI in the world. Fast Field-Cycling MRI switches rapidly over a arrange of field strengths (0.2 T to 200uT), providing a T1 dispersion curve. This information is invisible to fixed-field scanners and uncovers unique knowledge about motion and interaction between component molecules within a tissue (i.e. water/fat/proteins). In this application we wish to use our in-house expertise further to extend the capability of our Fast Field-Cycling MRI to perform cardiac imaging by building the first-ever cardiac Fast Field-Cycling MRI coil and develop cardiac pulse sequences with ECG gating. We aim to establish the normalcy of T1 dispersion curves for left ventricular myocardium in healthy volunteers, and further on to distinguish the characteristics of post-myocardial infarction scar T1 dispersion curves.
REC name
North of Scotland Research Ethics Committee 1
REC reference
20/NS/0042
Date of REC Opinion
27 Mar 2020
REC opinion
Favourable Opinion