The Role of Body Composition in Colorectal Cancer Outcomes

• Research type

  Research Database

• IRAS ID

  109465

• Research summary

  Cancer of Colon and Rectum (CACOLREC) Database

• REC name

  London - South East Research Ethics Committee

• REC reference

  18/LO/0058

• Date of REC Opinion

  29 Mar 2018

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  This study aims to establish the relationship between body composition i.e the proportion of fat and muscle in a human body and surgical outcomes in patients with colorectal cancer. The study population of this research project includes all patients that were treated for colorectal cancer from 2006 to 2020 at NWLUH NHS trust. The data counted in in the study are: demographic, preoperative, operative data, post-operative data, pathology, oncology, body composition, imaging and follow up data. All identifiable information will be anonymised prior to storage in password-locked NHS computers. Only members of the research team will have access to these stored data.

• Research programme

  We will perform an observational study, aiming to answer the question regarding the relationship between body composition and colorectal cancer. We will test whether body composition is associated with short-term outcomes, length of hospital stay, patient demographics, how body composition changes over the course of treatment and the impact on long term outcomes. If it is identified that the body composition, a modifiable condition of a patient perioperatively is related to the prognosis and the outcomes of its cancer disease, it is likely to confer multiple benefits to both cancer patients and the National Health Service.

• Research database title

  Cancer of Colon and Rectum (CACOLREC) Database

• Establishment organisation

  London North West University Healthcare NHS Trust

• Establishment organisation address

  St Mark's Hospital, Watford Road

  Harrow

  London

  HA13UJ