The relationship between serum sodium concentration and albuminuria
Research type
Research Study
Full title
The association between serum sodium concentration and albuminuria: a retrospective cohort study
IRAS ID
261679
Contact name
Nicholas Cole
Contact email
Sponsor organisation
Epsom and St Helier NHS Trust
Duration of Study in the UK
0 years, 3 months, 1 days
Research summary
Small amounts of albumin (a protein) in the urine is thought to represent damage to the lining of blood vessels and is closely linked with the risk of cardiovascular disease, including heart disease and strokes. Reducing the amount of salt in our diet helps to lower the amount of albumin in the urine and cardiovascular risk. The mechanisms are not fully understood but the concentration of sodium in our blood might be important: previous studies have shown that eating more salt can lead to small increases in the blood sodium concentration, and that can be detrimental for the function of blood vessels. Therefore, this study aims to be the first to find out whether people with higher concentrations of sodium in the blood have a greater risk of having albumin detected in their urine. It will do this by examining the electronic health records of patients from General Practitioner practices around the United Kingdom.
REC name
North West - Greater Manchester West Research Ethics Committee
REC reference
19/NW/0143
Date of REC Opinion
25 Feb 2019
REC opinion
Favourable Opinion