The Popular Age Registry

  • Research type

    Research Study

  • Full title

    Registry of elderly patients with non-ST-elevation myocardial infarction: The popular age registry

  • IRAS ID

    234434

  • Contact name

    Robert Storey

  • Contact email

    R.F.Storey@sheffield.ac.uk

  • Sponsor organisation

    St. Antonius Hospital

  • Duration of Study in the UK

    1 years, 0 months, 31 days

  • Research summary

    Patients who have had a type of heart attack, known medically as a Non-ST-elevation Myocardial Infarction (NSTEMI), will be require to take blood thinners. These blood thinners are referred to as dual antiplatelet therapy or, DAPT. The objective to taking these medications is to prevent recurrent cardiovascular problems arising from the blood clotting. In addition to these medications, invasive treatment is the preferred strategy for most NSTEMI patients.

    Elderly patients with a NSTEMI constitute a specific group of patients as they are at higher risk of serious future cardiovascular events, as well as treatment related complications (especially bleeding) due to frailty and comorbidities such as renal failure.8

    Although many patients presenting with this type of heart attached are elderly, in the many randomized trials in this area, the representation of these elderly patients is low. This has lead to a major gap in the knowledge regarding the best treatments in this patient group.

    Objective:
    1) To describe the elderly patients hospitalised for a NSTEMI and to identify early indicators where the patient may develop a major adverse event such as future cardiovascular problems, cerebrovascular events, such as a stroke and bleeding.
    2) To describe the medical therapy and invasive treatment choices made in this elderly patient group, determining predictors for the prescription of blood thinning agents and determining predictors for quality of life.

  • REC name

    London - Harrow Research Ethics Committee

  • REC reference

    18/LO/0028

  • Date of REC Opinion

    7 Mar 2018

  • REC opinion

    Further Information Favourable Opinion