The POPPY study
Research type
Research Study
Full title
Preconception to pOst-partum study of cardiometabolic health in Primigravid PregnancY: POPPY
IRAS ID
301910
Contact name
Ian Wilkinson
Contact email
Sponsor organisation
Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
Duration of Study in the UK
4 years, 11 months, 31 days
Research summary
Women who experience placental complications during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth restriction (baby being small) are at a two-fold higher risk of developing heart disease and diabetes later in life compared to women who do not. We do not know whether such complications cause heart disease and diabetes directly, or whether these complications happen in women who already have poorer health before pregnancy. We will assess risk factors for heart disease and diabetes in women actively trying to conceive before and during pregnancy, and 9-12 months after delivery to see whether placental complications make a difference to their heart health. This will allow us to understand if, and how, placental complications increase the risk of heart disease and diabetes, and, therefore, how best to reduce this risk and potentially prevent placental complications in the future.
REC name
London - Queen Square Research Ethics Committee
REC reference
22/PR/1530
Date of REC Opinion
23 Mar 2023
REC opinion
Further Information Favourable Opinion