The PEPEX Study

  • Research type

    Research Study

  • Full title

    Does the undertaking of a session of physiotherapy (PEP and Autogenic Drainage) prior to exercise improve exercise performance?

  • IRAS ID

    160316

  • Contact name

    Donald Urquhart

  • Contact email

    don.urquhart@nhslothian.scot.nhs.uk

  • Sponsor organisation

    Research and Development Department

  • Research summary

    The aim of this study is to evaluate whether airway clearance physiotherapy immediately before exercise improves exercise performance as measured by Cardiopulmonary Exercise Testing (CPET)in children with Cystic Fibrosis (CF). The aim is to recruit 50 children over 10 years old from a convenience sample of those children with CF attending the Royal Hospital for Sick Children Edinburgh CF Clinic. Subjects will be randomised to either a sequence of airway clearance therapy (ACT) or no ACT immediately prior to exercise test 1 and the opposite sequence will be undertaken prior test 2. The results of the exercise tests (with or without prior physiotherapy) will be compared.

  • REC name

    North West - Preston Research Ethics Committee

  • REC reference

    14/NW/1270

  • Date of REC Opinion

    28 Oct 2014

  • REC opinion

    Further Information Favourable Opinion