Brain Tissue Donation for Research into Neurodegenerative Diseases
Research type
Research Tissue Bank
IRAS ID
134391
Contact name
David Mann
Contact email
Research summary
The Manchester Brain Bank
REC name
North East - Newcastle & North Tyneside 1 Research Ethics Committee
REC reference
09/h0906/52+5
Date of REC Opinion
6 May 2014
REC opinion
Further Information Favourable Opinion
Data collection arrangements
Tissues stored within the Manchester Brain Bank are located within the Clinical Sciences Building at Salford Royal Hospital. These include:- Fixed, paraffin embedded and frozen brain and spinal cord tissue and in some cases small samples of other tissues along with and CSF, are collected at autopsy with full informed consent from:
- clinically well-characterised donors suffering from a range of dementias, neurodegenerative and vascular disorders and occasionally related psychiatric or genetic disorders largely via prospective clinical studies within the Cerebral Function Unit but also via national initiatives such as Brains for Dementia Research.
- volunteer normal control donors largely with clinical assessment during life
Research programme
The Manchester Brain Bank is an open access tissue bank supplying tissue for projects into the functioning of the brain and nervous system in particular in the field of brain ageing,age-related disease and neurodegenerative disease. Potential donors with such disorders and normal controls are recruited mainly through clinical research programmes. Samples are supplied for work including molecular and biochemical studies and genetics. Diseases studied will include dementias,cerebrovascular disease, neurodegenerative diseases, some psychiatric disorders, stroke, epilepsy, traumatic brain injury and some brain tumours. Samples are provided to any applicants who can demonstrate that their project is scientifically and ethically valid.
Storage license
12291
RTBTitle
The Manchester Brain Bank
Establishment organisation
University of Manchester
Establishment organisation address
Oxford Road
Manchester
M13 9PL