The HAPI Study
Research type
Research Study
Full title
Does the Corin Optimised Positioning System improve clinical outcome in total hip arthroplasty? A multi-centre, two-arm randomised control trial
IRAS ID
216084
Contact name
Sue King
Contact email
Sponsor organisation
University of Oxford
Duration of Study in the UK
3 years, 3 months, 1 days
Research summary
We aim to investigate whether the use of the Corin Optimised Positioning System (OPS) for implant positioning during total hip replacement (THR) is superior to current implant positioning practice during THR by way of a randomised controlled trial comparing the two.
At present, the dislocation rate after THR reported in Joint Registries is between 1 and 3%, with studies reporting a dislocation rate as high as 15%. A recent study showed that 58% of patients who had suffered dislocation after THR had implants judged to be in a safe position. This has led to suggestions that the previous idea of one generic 'safe zone' may be misleading, and instead there is a unique optimum position to place the prosthetic cup in each patient undergoing THR, based on the unique interaction of their spine and pelvis.
The Corin OPS is a new technique designed to enable delivery of the prosthetic cup into the optimum position for each patient. Dynamic preoperative imaging allows creation of a model, which facilitates accurate placement of the cup.
We will perform a randomised controlled trial of 476 patients. 238 will receive THR will conventional positioning; the other 238 will receive THR with Corin OPS to guide positioning. Patients will be aged 18-85 years, listed for THR at a participating site. Primary outcome will be dislocation rate at 1 year. We predict recruitment will take 2 years. The study will be funded by Corin PLC
REC name
South Central - Oxford B Research Ethics Committee
REC reference
17/SC/0506
Date of REC Opinion
4 Dec 2017
REC opinion
Further Information Favourable Opinion