The EXACT Trial
Research type
Research Study
Full title
Evaluation of X-ray, Acetabular Guides and CT in Total Hip Replacement
IRAS ID
218310
Contact name
Richard King
Contact email
Sponsor organisation
University Hospitals Coventry and Warwickshire NHS Trust
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
33273, ISRCTN pending
Duration of Study in the UK
2 years, 6 months, 3 days
Research summary
Total hip replacement is one of the most successful surgical procedures of modern times, with over 80,000 performed each year in the UK. However, up to 5% of all primary hip replacements need to be revised within the first 10 years, and in many cases malposition of the acetabular (hip socket) component is implicated in the early failure. The standard method of positioning the acetabular component is for the surgeon to be guided by a combination of the visible anatomical landmarks within the surgical field, and the wider environment of the operating theatre. The advent of 3D printing has led to the development of custom-made surgical guides which can be used during surgery, in order to assist the surgeon in the positioning of instruments and devices. These surgical guides are manufactured based on CT or MRI imaging, and are designed to clearly indicate to the surgeon the desired location and orientation of bony cuts and implant positions. This study will test the hypothesis that an acetabular alignment guide combined with three-dimensional CT-based planning using the Corin OPS™ (Optimised Positioning System), provides more accurate component alignment following primary total hip replacement compared with the current standard treatment, with the aim of improving patient outcomes and reducing the risk of complications of total hip replacement.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
17/WM/0261
Date of REC Opinion
1 Sep 2017
REC opinion
Further Information Favourable Opinion