The effects of SAPS fluid pressure on kidney function post operatively
Research type
Research Study
Full title
A pilot study about the effects of the pressure generated by the SAPS (Single Action Pumping System) irrigation flow during ureterorenoscopy on the kidney function post-operatively.
IRAS ID
217846
Contact name
Antonia Hardcastle
Contact email
Sponsor organisation
Queen Elizabeth Hospital
Duration of Study in the UK
1 years, 0 months, days
Research summary
The rationale for this research topic is to find out whether the increased intra-renal pressure generated by the irrigation fluid flow during ureterorenoscopy procedures is associated with a fall in the kidney function post operatively. Ureterorenoscopy is a commonly performed urological procedure that involves using a telescope that allows the surgeon to look into the ureter and the kidney to make a diagnosis and give treatment when necessary. Irrigation fluid is used to improve visibility and is implicit for a successful procedure. In many of these procedures an operator dependent single action pumping system is used to provide controlled irrigation through the endoscope. The pumping system delivers the desired amount of fluid required to improve visibility at various pressures depending on the force applied while pumping.
The study proposes to do a continuous measurement of the fluid pressures generated by the irrigation fluid throughout ureterorenoscopy procedures by attaching a pressure monitor immediately after the fluid source. Following ureterorenoscopy, two measurements of the kidney function would be obtained ideally with the first being within the first 24 hours post-op then the second being within two weeks after the operation. Finally, the aim is to find a relationship between high pressures and a drop in the kidney function. The selected patients would already have their kidney function measured at the pre-operative assessment. The study would like to recruit adults undergoing ureterorenoscopy in the department of urology in the Queen Elizabeth Hospital King’s Lynn for the period of up to 12 months.REC name
London - Fulham Research Ethics Committee
REC reference
17/LO/0507
Date of REC Opinion
23 Mar 2017
REC opinion
Favourable Opinion