The effects of neuromuscular block reversal agents on ICP
Research type
Research Study
Full title
The effect of drugs used to reverse neuromuscular blockade on intra-cranial pressure
IRAS ID
16863
Contact name
Iain Moppett
Contact email
Sponsor organisation
University of Nottingham
Eudract number
2009-011696-68
ISRCTN Number
n/sa
Clinicaltrials.gov Identifier
n/a
Research summary
Patients undergoing surgery on the head are very often given drugs during anaesthesia to paralyse their muscles so that they do not move or cough during surgery. At the end of the operation these paralysing drugs are either allowed to wear off on their own, or a drug is given to make the effects wear off more quickly. Recently a new drug (sugammadex) has been introduced. It is licensed for use in neurosurgery but we would like to make sure that it has no effects on the pressure inside the head after operations. We want to compare it to the drug combination that was previously used (neostigmine / glycopyrollate).
REC name
East Midlands - Nottingham 2 Research Ethics Committee
REC reference
09/H0408/72
Date of REC Opinion
10 Jul 2009
REC opinion
Favourable Opinion