The Effect of Statins in Patients with COPD

• Research type

  Research Study

• Full title

  The Cardiovascular and Inflammatory Effects of Statin Therapy in Patients with COPD

• IRAS ID

  41340

• Contact name

  Charlotte Bolton

• Eudract number

  2009-017689-22

• ISRCTN Number

  n/a

• Clinicaltrials.gov Identifier

  n/a

• Research summary

  Cardiovascular disease is a major cause of morbidity and mortality in patients with the lung disease called COPD, over and above the effect of smoking which is common to both. This may be due to inflammation in either the airways or in the circulation. Current therapy for COPD addresses the breathlessness but new treatments need to address the cardiovascular risk. We wish to explore the role of the drug - simvastatin, which is known to lower cholesterol but which may also reduce risk in those with a normal lipid level.

• REC name

  East Midlands - Nottingham 2 Research Ethics Committee

• REC reference

  10/H0408/10

• Date of REC Opinion

  20 Apr 2010

• REC opinion

  Further Information Favourable Opinion