The effect of morphine on prasugrel absorption in STEMI patients

• Research type

  Research Study

• Full title

  Study of the effect of morphine on prasugrel absorption in patients with prior history of ST elevation myocardial infarction

• IRAS ID

  84707

• Contact name

  Allison Morton

• Eudract number

  2011-003320-12

• Research summary

  Heart Attacks are a major cause of death in this country. When patients have a heart attack, they are treated with anti-clotting drugs, one of which is a drug called Prasugrel. It is important that Prasugrel starts to work as quickly as possible following a heart attack. As many patients who have a heart attack experience excruciating pain, they are often given morphine (a strong painkiller) by the Ambulance crew. We think that morphine may affect how Prasugrel is absorbed from the stomach and may delay how quickly it starts to work. We intend to study the effect of morphine on the absorption of Prasugrel.

• REC name

  Yorkshire & The Humber - Sheffield Research Ethics Committee

• REC reference

  11/YH/0387

• Date of REC Opinion

  17 Nov 2011

• REC opinion

  Favourable Opinion