The effect of 670nm Light on Visual Function in Aging and AMD
Research type
Research Study
Full title
A pilot study to investigate the effect of 670nm light on visual function in aging and age related macular degeneration
IRAS ID
183202
Contact name
Sobha Sivaprasad
Contact email
Sponsor organisation
University College London
Clinicaltrials.gov Identifier
Z6364106/2015/01/43, Data protection number
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Photoreceptors (cells which convert light to an electric signal) in the retina (the sensory layer in the back of the eye) demand more energy than other tissue in the body. Unfortunately, as we grow older, the energy producing units in our cells (mitochondria) become less efficient and produce less energy. This is associated with inflammation (the body’s response to an insult) which we think contributes to age-related macular degeneration (AMD) and aging in general. AMD is the commonest cause of blindness in the elderly and unfortunately, there is no prevention or cure for this.
A molecule in mitochondria can absorb a particular wavelength of light (670nm – which is red) and increase energy production. This has been shown in different cells, including the retina. Studies have also shown that inflammation associated with aging and AMD is reduced by exposure to this red light.
This is a pilot study to see if exposure to 670nm wavelength of light can improve visual function in aging and age related macular degeneration. Participants will hold a device emitting this red light to their eyes for one minute every day for one year and have their retinal function measured before and after.
REC name
London - Stanmore Research Ethics Committee
REC reference
16/LO/2022
Date of REC Opinion
24 Jan 2017
REC opinion
Further Information Favourable Opinion