The Clinch Token Transfer Test (C3T)
Research type
Research Study
Full title
Developing clinical applications for a novel multi-task funcational assessment: The Clinch Token Transfer Test (C3T)
IRAS ID
217937
Contact name
Monica Busse
Contact email
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Huntington’s disease (HD) is an inherited brain disorder. Over time people with HD experience worsening problems with movement, thinking and behaviour. To date it has been very difficult to develop accurate tests that can measure subtle differences in people with HD and that can measure how they get worse as their disease progresses. It is really important to have a reliable test that can measure changes in people with HD so that we can test and compare new treatments.\nThe Clinch Token Transfer Test (C3T) has been developed to test how well a person can do certain tasks. Participants have to pick up and move tokens of different sizes from one hand to another before putting them into a moneybox. The task can be made more difficult in two ways. We measure how long participants take and record the number of mistakes they make, giving a total score for the test. In HD patients, the C3T has been found to show differences between people in different stages of HD in a similar way to the ‘gold standard’ tests that already used. \nThis study is aimed at improving the C3T equipment so that it can be used for a long periods of time in studies such as clinical trials. The C3T might also be useful in brain disorders but this needs to be investigated. Therefore, this study also aims to test the usefulness of the C3T in Parkinson’s Disease and Juvenile Myoclonic Epilepsy. Participants will be asked to complete the C3T and some other clinical tests that are specific to each disorder which can tell us more about each participant. Participants will also be invited to attend an optional follow up assessment visit after 4 weeks so we can see how reliable our measurements are.\n
REC name
Wales REC 3
REC reference
17/WA/0014
Date of REC Opinion
23 Feb 2017
REC opinion
Further Information Favourable Opinion