The BRIGHT study
Research type
Research Study
Full title
Safety and efficacy of shorter ablation times to the posterior wall during pulmonary vein isolation with a multielectrode radiofrequency balloon catheter
IRAS ID
328017
Contact name
John Silberbauer
Contact email
Sponsor organisation
University Hospitals Sussex NHS Foundation Trust
Duration of Study in the UK
1 years, 7 months, 31 days
Research summary
Atrial fibrillation (AF) is the most common clinical cardiac rhythm disturbance affecting 1 in 200 people regardless of age. At present, standard care involves a procedure called an ablation. Small burn marks are made inside
the heart in an attempt to correct the irregular heart beat. The main goal of AF ablation is isolating the electrical signals from the pulmonary veins that enter the left upper heart chamber (atrium). Delivering this energy with balloon catheters have demonstrated a shorter learning curve and reduced procedural time. The new multi pole ablation balloon (Heliostar) has demonstrated to be a safe and effective tool for AF abation. The posterior wall of the left atrium is adjacent to the oesophagus and a rare and severe complication is a connection between both structures (fistula). Bylimiting energy to the posterior wall and hence to the oesophagus there should be a reduced chance of fistula formation. This study will assess a new reduced energy delivery time, to the posterior wall, to achieve pulmonary vein isolation and assess safety by monitoring for any oesophageal injury through temperature monitoring and a post procedural gastroscopy.REC name
London - Harrow Research Ethics Committee
REC reference
23/PR/1010
Date of REC Opinion
26 Oct 2023
REC opinion
Further Information Favourable Opinion