The Back of the Brain Project (BoB)

  • Research type

    Research Study

  • Full title

    The Back of the Brain project (BoB): A new approach to cerebral localisation of perceptual functions.

  • IRAS ID

    209574

  • Contact name

    Alex Leff

  • Contact email

    a.leff@ucl.ac.uk

  • Sponsor organisation

    University College London

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    Can learning affect the brain to the degree that specialized brain areas are created? Seemingly selective deficits in reading (pure alexia) following brain injury suggest that this is the case. In traditional studies, patients are selected based on their symptoms (alexia), which are then related to their brain lesions.

    Here, we instead propose selecting a large group of patients based on the localization of their brain lesion. We then investigate their perceptual and reading performance using a comprehensive experimental test-battery in a cross-sectional study. By characterising the profiles of these patients, and relating these to the underlying lesion (as identified using MRI brain scanning), the project will provide new knowledge about how reading performance may affect the organisation of other visual perceptual functions (e.g.: face and object perception). The same functions will also be investigated in a large sample of normal subjects, to test the hypothesis that learning to read systematically affects other perceptual skills.

  • REC name

    East Midlands - Leicester Central Research Ethics Committee

  • REC reference

    16/EM/0348

  • Date of REC Opinion

    15 Sep 2016

  • REC opinion

    Further Information Favourable Opinion