The association between pain and poor function after knee replacement
Research type
Research Study
Full title
The association between pre-operative pain psychology and hypersensitivity with poor functional outcome after knee replacement
IRAS ID
232013
Contact name
Bodor Bin Sheeha
Contact email
Sponsor organisation
University of Salford
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
NCT03132064, The Association Between Pre-operative Pain Psychology and Hypersensitivity With Poor Functional Outcome After Knee Replacement.
Duration of Study in the UK
1 years, 1 months, 0 days
Research summary
To explore whether there are factors that help us to understand why some patient outcomes are not successful and identify prediction factors for progression. Assess central pain sensitisation and psychology pre- and post-surgery with reliable tools that explore prediction tools for good/poor progression and improve patient selection, patient preparation and timing for surgery (Bade, Wolfe, Zeni, Stevens-Lapsley, & Snyder-Mackler, 2012; Lungu, Desmeules, Dionne, Belzile, & Vendittoli, 2014).
The aim of this project is to explore the effects of pre-surgical central pain sensitisation on functional outcomes post-TKA. Central pain sensitisation will be assessed using pressure algometry and the Pain Catastrophizing Scale will be used to explore pain psychology. Functional outcomes post-TKA will be assessed using a commonly used scale for patients’ self-reported outcomes (Oxford Knee Score), visual analogue scale, a star excursion balance test, four recommended patient performance-based tests and physical activity.To gain an understanding of recovery post-TKA and explore whether there are factors that can help us to understand why some patient outcomes are not successful and identify predictive factors for progression: a prospective study measuring outcomes 6 months post-TKA with the following objectives;
• Explore the effects of preoperational central pain sensitisation using pressure algometry and possible correlation with post-TKA pain and Oxford Knee Score, balance, functional performance tests and physical activity.
• Explore preoperational psychological pain factors using the Pain Catastrophizing Scale for outcomes after TKA in terms of pain, Oxford Knee Score, balance, functional performance tests and physical activity.REC name
London - Dulwich Research Ethics Committee
REC reference
17/LO/1315
Date of REC Opinion
15 Aug 2017
REC opinion
Further Information Favourable Opinion