The association between depression and Type 2 diabetes. Version 3
Research type
Research Study
Full title
The association between depression and Type 2 diabetes. A case control study comprising adults in England.
IRAS ID
322219
Contact name
Namra Amin
Contact email
Sponsor organisation
Glasgow Caledonian University
Duration of Study in the UK
0 years, 5 months, 1 days
Research summary
The nature of this research area is to conduct a proposed case control study that determines the association between depression and type 2 diabetes and the risk factors associated with these two disorders. The proposed study serves the purpose in highlighting the association between depression and type 2 diabetes in both men and women. It aims to explore the direction of the association between depression and type 2 diabetes. The proposed research will use observational study design following quantitative research method comprising the sample size of 155 participants in each of the case and control groups with a total of 310 participants in sample size. Data collection will be performed after selection of participants from University Hospitals of Morecambe Bay NHS Foundation Trust specifically from Westmorland General Hospital using convenience sampling method. This study will use previously developed and evaluated PHQ-9 scale and Finnish Diabetes Risk Score (FINDRISC) as screening instruments, severity measures and risk predictor for the development of depression and type 2 diabetes. This study will aid in providing the evidence on risk of diabetes and depression that may be mediated by biological and psychological mechanisms. Additionally, the findings of this study will suggest that the underlying source and nature of diabetes and depression may have the similar basis. The results obtained from the study will further help in producing effective and innovative multidisciplinary approaches for depression and lifestyle behaviours to prevent the development of type 2 diabetes. It will also encourage the careful monitoring of depression in diabetics and for diabetes in depressive patients. Moreover, these approaches can also help in earlier detection and initiation for the treatment of both disorders especially if they occur in comorbidity. The research will be reviewed by Glasgow Caledonian University REC and NHS REC.
REC name
South Central - Oxford A Research Ethics Committee
REC reference
23/SC/0365
Date of REC Opinion
4 Oct 2023
REC opinion
Unfavourable Opinion