The APPLE Study.
Research type
Research Study
Full title
The Asking People with Psoriasis about Lifestyle and Eating (APPLE) Study.
IRAS ID
324671
Contact name
Wendy Hall
Contact email
Sponsor organisation
King's College London
Clinicaltrials.gov Identifier
NCT05448352, ClinicalTrials.gov
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
Psoriasis is an inflammatory skin condition affecting 2% of the UK population. It exerts a multi-faceted impact on life quality. The onset of psoriasis is driven by gene and environmental factors. Consequent to research condemning the ‘Western diet’ for the rise in inflammatory diseases, interest has emerged to understand if diet influences the severity of psoriasis.
To provide evidence-based dietary and lifestyle advice, it is of critical importance to first understand the current dietary and lifestyle patterns in a population with psoriasis. Insights on habitual dietary and lifestyle patterns amongst individuals with psoriasis is scarce. To our knowledge, only one study in the United States has explored the role of diet and diet related behaviours in a population with psoriasis.
The APPLE study will be the first study to capture the current dietary and lifestyle patterns of individuals living with psoriasis in the United Kingdom. This study is funded by the Psoriasis Association and will address the first research priority set by the James Lind Alliance.
Volunteers will be eligible to participate if they are adults (18+ years), with a psoriasis diagnosis (inclusive of all subtypes), residing in the United Kingdom, and who are able to complete surveys in English.
The APPLE study is an online study to be completed on a laptop/computer device. Volunteers will first be invited to read an information sheet, provide consent to participate, and answer a short eligibility questionnaire. Participation in this study will involve the completion of a multiple-choice survey with questions on general health, sleep, physical activity, psoriasis severity and diet, as well recording food and beverage intakes in a series of online diet diaries.
REC name
London - Westminster Research Ethics Committee
REC reference
23/LO/0536
Date of REC Opinion
4 Jul 2023
REC opinion
Favourable Opinion