Testing the psychometric properties of the APPRAISE PROM
Research type
Research Study
Full title
Testing the psychometric properties of a new patient-reported outcome measure to assess the outcomes of prolapse, incontinence, and mesh complication surgery: The APPRAISE Study.
IRAS ID
329856
Contact name
Georgina Jones
Contact email
Sponsor organisation
Leeds Beckett University
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Aim: The APPRAISE study aims to develop a new patient-reported outcome measure (PROM) to better allow women to report adverse outcomes and quality-of-life impacts following surgery for pelvic organ prolapse (POP), stress urinary incontinence (SUI) and mesh complications. This work package will follow two systematic reviews; an interview study exploring experiences of surgery for POP, SUI or mesh complications; and a study assessing the user acceptability of the prototype versions (paper and electric) of the new PROM. Following the first version of the PROM being developed, the purpose of this study is to evaluate its psychometric properties.
Background: Different surgical treatments are available to treat POP and SUI, one of which uses polypropylene mesh (a synthetic material used to reinforce natural tissues in the pelvic floor). Some women who had mesh surgery experienced complications which required further corrective surgery. This had negative effects on their quality of life, and their experiences of using urogynaecology services. However, there is currently no surgery-specific patient-reported outcome measure (PROM) available for these women to tell us about the effects of pelvic floor surgery on their quality of life. Our research is addressing this, by developing a PROM to compare outcomes for the different surgical treatments for POP, SUI and mesh complications that captures the full range of effects on quality of life.
Methods: The PROM will be administered to different samples of patients across four surveys, to evaluate its psychometric properties and to test the PROM in the context of short-term outcomes, long-term outcomes, and a clinical trial.
Outputs: Our study findings will be shared across social media and mainstream media outlets using lay summaries, infographics and a YouTube video, at healthcare and academic conferences, in leading academic journals and with relevant third sector parties (e.g. British Society of Urogynaecology, Bladder and Bowel UK).
REC name
East Midlands - Leicester South Research Ethics Committee
REC reference
24/EM/0007
Date of REC Opinion
4 Apr 2024
REC opinion
Further Information Favourable Opinion