Systems Biology of Coronary Artery Ectasia

  • Research type

    Research Study

  • Full title

    Systems biology application in plasma and urine of patients with coronary artery ectasia.

  • IRAS ID

    121920

  • Contact name

    Elaine Holmes

  • Contact email

    elaine.holmes@imperial.ac.uk

  • Sponsor organisation

    Imperial College London

  • Research summary

    The current project will be a systems biology study, based on metabonomic technologies in patient biological fluids. It will additionally include a panel of proteins to be quantified in biofluids. The biofluids involved are plasma and urine. The study will be carried out on three groups of patients that were admitted to the hospitals with chest pain symptoms. Patients with 1) coronary artery ectasia (diffuse dilatation), 2)coronary artery ectasia with evidence of minimal atherosclerosis, and 3) matched group of patients with normal coronary arteries. \n

  • REC name

    East of England - Cambridgeshire and Hertfordshire Research Ethics Committee

  • REC reference

    14/EE/0134

  • Date of REC Opinion

    31 Mar 2014

  • REC opinion

    Favourable Opinion