Streamlining cross-sectional imaging pathways (SCIPs)
Research type
Research Study
Full title
Streamlining cross-sectional imaging pathways (SCIPs): A feasibility and economic modelling study of point of care creatinine testing in radiology.
IRAS ID
215388
Contact name
Beverly Snaith
Contact email
Sponsor organisation
Mid Yorkshire Hospitals NHS Trust
Duration of Study in the UK
0 years, 9 months, 0 days
Research summary
We will document the care pathway (steps) for patients referred for CT scan for cancer. A key part of the pathway is a blood test to check how well the kidneys are working (renal function) before they can have an injection of x-ray dye with the scan. To examine opportunities to streamline the pathway this study examines the feasibility of using a point of care blood test (PoCT) performed in radiology rather than the standard laboratory test. We will also build a computer-based economic model to compare the cost of the different blood test options.
To ensure the PoCT is accepted in practice and to inform the economic model we will evaluate the test on 300 patients referred for CT on a cancer pathway. They will be consented to have an additional blood test at the time of the scan to test on the PoC machine and in the laboratory. They will also have a follow up blood test 2-3 days after the scan to check whether the x-ray dye has affected the function of the kidneys.
This feasibility study will quantify the number of patients who would be affected by the change to PoCT and establish test failure rates. We will compare the results of the PoCT to standard laboratory test and estimate bias to allow a decision algorithm for test results to be developed. This will establish the patient management processes for different renal function levels, providing assurance to clinicians of the concordance of the tests and confirm the parameters for any preventative measures to reduce CI-AKI risk, such as intravenous or oral fluids. This feasibility assessment will also identify staff training needs to undertake the PoCT, including the potential for this to be undertaken by unregistered clinical support staff.REC name
Yorkshire & The Humber - Sheffield Research Ethics Committee
REC reference
16/YH/0520
Date of REC Opinion
22 Dec 2016
REC opinion
Favourable Opinion