Statistical Modelling and Reconstruction of the Hip Joint

  • Research type

    Research Study

  • Full title

    Statistical Modelling and Reconstruction of the Hip Joint

  • IRAS ID

    225933

  • Contact name

    J. Mark Wilkinson

  • Contact email

    j.m.wilkinson@sheffield.ac.uk

  • Sponsor organisation

    Sheffield Teaching Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    2 years, 9 months, 24 days

  • Research summary

    Hip replacement surgery is commonly carried out in patients with a damaged hip joint, for example when they have arthritis. It involves the replacement of the damaged hip joint with an artificial one called an implant. In recent years, there has been a rise in the number of hip replacement surgeries. In 2015 alone, about 100 000 of these operations were performed in England, Wales, Northern Ireland and the Isle of Man. After ten years, about 1 in 20 patients are expected to need repeat surgery to replace their previous implant. After this first repeat surgery, it is likely that more will be needed. Repeat surgery is challenging, as the patient loses more bone and has more scarring with each further operation. They may need specially-made ‘custom’ implants to fill the holes in their bone.

    The Centre for Computational Imaging and Simulation Technologies in Biomedicine together with the Mellanby Centre for Bone Research at The University of Sheffield aim to develop a method which will automatically design custom hip implants for use during repeat surgery. With this project, we will give the first step towards that end. We will develop special x-ray scan models of a normal hip and use these as templates from which to reconstruct the missing hip bone using an automatic method. We will take these scans from the existing x-ray archives at Sheffield Teaching Hospitals NHS Foundation Trust. We will also use previously collected scans from patients prior to repeat surgery to design the custom implant models.

    Through this work, we look to develop a reconstruction method that will be the first step that will ultimately allow us to offer patients custom hip implants that better fit their individual pattern of bone loss. These could be used in situations where surgery would otherwise be very difficult.

  • REC name

    London - Westminster Research Ethics Committee

  • REC reference

    18/LO/0670

  • Date of REC Opinion

    24 Apr 2018

  • REC opinion

    Favourable Opinion